About the Core Facility
The UC Berkeley Genotyping & Methylation Core offers comprehensive array-based genomics services with expertise in high-throughput Illumina workflows.
Illumina Array Platform
Infinium assay ecosystem for reproducible SNP genotyping and CpG methylation at single-nucleotide resolution.
Genotyping · MethylationBiospecimen Expertise
EDTA blood, PAXgene blood, Oragene saliva, and buffy coat ensuring optimal nucleic acid quality.
Blood · Saliva · Buffy CoatFlexible Pricing
Flat rates for standardized services. Custom quotes for complex projects.
Flat Rate · Custom QuoteIllumina Array Processing
End-to-end processing — whole-genome amplification through scanning and data delivery.
Methylation Profiling
Interrogate the human methylome using the Infinium MethylationEPIC v2.0 BeadChip.
Infinium MethylationEPIC v2.0
Covers >935,000 CpG sites including promoters, enhancers, and CpG islands.
935K CpG · EWAS · ClocksKey Applications
- Epigenome-wide association studies (EWAS)
- Differential methylation regions (DMRs)
- Epigenetic age / biological clocks
- Cancer epigenomics
- Cell-type deconvolution
- Copy-number variation (CNV)
- Single-nucleotide resolution
- Bisulfite + two-channel chemistry
- R² > 0.99 reproducibility
- FFPE compatible (≥250 ng)
- 8 samples per BeadChip
- Conversion efficiency QC report
- IDAT & CSV delivery
- Analysis pipeline on request
Genotyping Arrays
Genome-wide SNP genotyping for GWAS, pharmacogenomics, and population genetics.
Global Screening Array (GSA)
Covers >654,000 SNPs optimized for global diversity and pharmacogenomics.
654K SNPs · GWAS · PGxCustom Arrays
We accommodate a range of Illumina BeadChip formats and custom content requirements.
Custom · Multi-EthnicBiospecimen Processing
From raw biospecimen to analysis-ready nucleic acids with stringent QC at every step.
DNA Extractions
High-quality genomic DNA isolation using validated protocols.
Blood · Saliva · Buffy CoatRNA Extractions
Total RNA with RIN assessment as standard QC.
Blood · PAXgeneQuantitation & QC
Qubit, PicoGreen, and NanoDrop measurements.
Qubit · NanoDropAliquoting & Plating
Normalization and 96-well plate formatting.
96-Well · Normalization- EDTA whole blood
- PAXgene stabilized blood
- Oragene saliva (DNA Genotek)
- Buffy coat
- Dried blood spots — on request
- Frozen tissue — selected types
How to Work With Us
From inquiry to data delivery in five simple steps.
Inquiry & Consult
Email us for a free consultation and quote.
Sample Submission
Submit with a completed sample manifest.
QC & Processing
Samples QC'd, extracted, normalized, arrayed.
Scanning & QC
BeadChips imaged and data QC performed.
Data Delivery
IDAT/CSV delivered securely with QC summary.
Pricing
Flat rates for routine services; custom quotes for complex projects.
Custom Pricing Available
Please contact us for a personalized quote.
| Service | Description | Rate | Notes |
|---|---|---|---|
| EPIC v2 Full Service | DNA QC, bisulfite conversion, hybridization, scan | Flat Rate | 8-sample minimum per chip |
| GSA Genotyping | DNA QC, hybridization, scan, genotype calls | Flat Rate | 8 or 24-sample formats |
| DNA Extraction — Blood | Genomic DNA from EDTA whole blood | Flat Rate | Includes Qubit QC |
| DNA Extraction — Saliva | Genomic DNA from Oragene saliva | Flat Rate | Includes quantitation |
| RNA Extraction | Total RNA from blood or select types | Custom Quote | RIN assessment included |
| Quantitation Only | Qubit / PicoGreen or NanoDrop | Flat Rate | Per sample |
| Normalization & Plating | 96-well plate formatting | Flat Rate | Per plate |
| Large-Scale (>96 samples) | Bulk / high-throughput campaigns | Custom Quote | Volume discounts may apply |
Get in Touch
Reach out to discuss your project or request a quote.
Facility Staff
Facility Manager
Submission & Inquiries
Contact us before submitting samples to confirm requirements and receive a sample manifest.